Evidence map›Paper›PMID 42540882›Full record

ArticleEJHaem2026

Infection Incidence and Survival in Patients With Multiple Myeloma and Chronic Lymphocytic Leukaemia: A Growing Concern in the Era of Modern Therapies.

Ingrid Glimelius, Love Tätting, Jonatan Freilich, M Natalia Stelmaszuk, Qian Yang, Anna Deleskog, Sigurður Y Kristinsson

Abstract read
In one paragraph

Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ingrid GlimeliusDepartment of Immunology, Genetics and Pathology, Cancer Precision Medicine Uppsala University Uppsala Sweden.
Love TättingDepartment of Haematology in Linköping and Department of Biomedical and Clinical Sciences Linköping University Linköping Sweden.
Jonatan FreilichAccess Consulting - RWE Parexel International Stockholm Sweden.
M Natalia StelmaszukAccess Consulting - RWE Parexel International Stockholm Sweden.
Qian YangRWE Consulting - Epidemiology & COA Parexel International Stockholm Sweden.
Anna DeleskogTakeda Pharma AB Stockholm Sweden.
Sigurður Y KristinssonFaculty of Medicine University of Iceland Reykjavik Iceland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Patients with multiple myeloma (MM) and chronic lymphocytic leukaemia (CLL) are burdened by immunodeficiency due to treatment and underlying disease. Infection-related mortality remains a significant concern for patients' overall survival (OS). Methods: This Swedish, population-based study examined incidence of infections and OS in patients with MM or CLL between January 2010 and December 2021, using Swedish Cancer Registry data. Results: Overall, 15,766 patients were included (MM: 8532; CLL: 7234); the majority were male (MM: 57%; CLL: 62%); median age was 71 years (range: 19-100 [MM]; 23-102 [CLL]). The proportion with a Charlson Comorbidity Index ≥ 5 was 37% (MM) and 25% (CLL). At least one infection was reported in 66% (MM; Conclusions: This study demonstrates high mortality rates among patients with MM and CLL, due to underlying malignancy and high infection burden. This emphasises the need for optimised anticancer treatments and infection control strategies. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.

Indexed as

chronic lymphocytic leukaemiaimmunodeficiencyinfectionsmultiple myeloma

Identifiers

PMID42540882
PMCPMC13426477

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.