Evidence map›Paper›PMID 42540736›Full record

ArticleJournal of asthma and allergy2026

A Functional Variant of

Xiangran Chen, Terence Yin Weng Lam, Yang Yie Sio, Yee-How Say, Kavita Reginald, Fook Tim Chew

Abstract read
In one paragraph

Article in Journal of asthma and allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiangran ChenDepartment of Biological Sciences, Faculty of Science, National University of Singapore, Singapore City, Singapore.ORCID 0009-0000-5496-2940
Terence Yin Weng LamDepartment of Biological Sciences, Faculty of Science, National University of Singapore, Singapore City, Singapore.
Yang Yie SioDepartment of Biological Sciences, Faculty of Science, National University of Singapore, Singapore City, Singapore.ORCID 0000-0002-3549-1706
Yee-How SayDepartment of Biological Sciences, Faculty of Science, National University of Singapore, Singapore City, Singapore.
Kavita ReginaldDepartment of Biomedical Sciences, Sir Jeffrey Cheah Sunway Medical School, Faculty of Medical and Life Sciences, Sunway University, Petaling Jaya, SEL, Malaysia.
Fook Tim ChewDepartment of Biological Sciences, Faculty of Science, National University of Singapore, Singapore City, Singapore.ORCID 0000-0003-1337-5146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We performed an integrative multi-omics analysis combining transcriptomic, genetic, and epigenetic data from peripheral blood mononuclear cells (PBMCs) of individuals in the Singapore/Malaysia Cross-Sectional Genetics and Epidemiological Study (SMCSGES) cohort. The influence of Results: The upregulation of Conclusion: This study identified rs2276921 and CpG sites cg23232844 and cg11969330 that regulate

Indexed as

asthmaCYP4V2DNA methylationeQTLPBMCSMCSGES

Identifiers

PMID42540736
PMCPMC13426356

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.