Evidence map›Paper›PMID 42540708›Full record

ArticleCureus2026

Noma Beyond Childhood: Dual-Flap Reconstruction of Orofacial Necrotising Infection in an Immunocompromised Elderly Male Patient.

Jevina Daphne Winnifred, Rohan Dsouza, Leo F Tauro

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jevina Daphne WinnifredGeneral Surgery, Father Muller Medical College Hospital, Mangalore, IND.
Rohan DsouzaGeneral Surgery, Father Muller Medical College Hospital, Mangalore, IND.
Leo F TauroGeneral Surgery, Father Muller Medical College Hospital, Mangalore, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancrum oris (noma) is a rapidly progressive orofacial gangrenous infection predominantly described in malnourished children. Its occurrence in immunocompromised elderly adults is rare, diagnostically challenging, and associated with high mortality rates without timely intervention. We report a case that highlights the general surgical principles governing its recognition and management. A 73-year-old man presented with a one-month history of right cheek swelling, ulceration, and trismus. Examination revealed an indurated, ulcerated lesion with purulent discharge and necrotic margins. Serial surgical debridements were performed, guided by culture-directed antibiotic therapy and concurrent nutritional rehabilitation. Definitive reconstruction was achieved with a right buccal mucosal advancement flap and cheek rotational fasciocutaneous flap. This case reaffirms that noma must be considered in elderly immunocompromised patients presenting with orofacial necrosis. A structured surgical strategy that includes aggressive debridement, broad-spectrum antimicrobial therapy, nutritional optimization, and staged locoregional reconstruction is the determinant of survival and functional recovery.

Indexed as

cancrum orischeek reconstructionimmunocompromisednomaorofacial necrosis

Identifiers

PMID42540708
PMCPMC13426527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.