ArticleArchives of medical science : AMS2026
C-reactive protein-albumin-lymphocyte (CALLY) index in chronic kidney disease and mortality: insights into inflammation, nutrition, and immune status.
Article in Archives of medical science : AMS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: The C-reactive protein-albumin-lymphocyte (CALLY) index represents a novel composite biomarker integrating inflammatory, nutritional, and immune parameters. We aimed to examine the relationship between CALLY index and chronic kidney disease (CKD) prevalence. Material and methods: This cross-sectional analysis utilized data from the National Health and Nutrition Examination Survey. CKD was defined as an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m Results: Among the 26 996 participants, 4997 individuals were diagnosed with CKD. Participants with CKD demonstrated lower CALLY index values compared to those without CKD. Multivariable logistic regression indicated that, compared to the lowest quartile, the highest quartile showed 29.5% reduced CKD risk (OR = 0.705, 95% CI: 0.589-0.845, Conclusions: The CALLY index demonstrates inverse associations with CKD risk and mortality, suggesting its potential utility as a comprehensive biomarker for CKD risk stratification and prognosis assessment.
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