Evidence map›Paper›PMID 42540482›Full record

ArticleThe Lancet regional health. Europe2026

Hospital acquisitions and 30-day mortality after acute myocardial infarction and stroke in Germany: a quasi-experimental cohort study.

Esra Eren Bayindir, Reinhard Busse, Jonas Schreyögg

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Article in The Lancet regional health. Europe, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Esra Eren BayindirHamburg Center for Health Economics, University of Hamburg, Hamburg, Germany.
Reinhard BusseDepartment of Health Care Management, Berlin University of Technology, Berlin, Germany.
Jonas SchreyöggHamburg Center for Health Economics, University of Hamburg, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hospital consolidation has intensified globally, but evidence regarding its association with clinical quality remains mixed, particularly in universal healthcare systems with regulated prices. We assessed whether hospital acquisitions were associated with changes in 30-day excess mortality for acute myocardial infarction (AMI) and stroke. Methods: This quasi-experimental cohort study used a staggered difference-in-differences design analyzing German hospitals providing AMI or stroke care (2009-2019). We compared performance changes three years pre- and post-acquisition between acquired hospitals (n = 125 for AMI; n = 121 for stroke) and control hospitals with stable ownership (n = 821 for AMI; n = 830 for stroke). Primary outcomes were 30-day excess mortality rates. Secondary outcomes included medical staffing intensity and the provision of cardiac catheterization laboratories and stroke units. Findings: Acquisition was associated with a 1.24 percentage-point (pp) decline in excess 30-day AMI mortality within three years (95% CI -2.04 to -0.44; p = 0.002). This improvement coincided with a 6.63 pp increase in the probability of providing cardiac catheterization laboratories (0.75 to 12.52; p = 0.03). For stroke, the association with excess 30-day mortality indicated a clinically relevant but statistically insignificant 0.43 pp decline (-1.38 to 0.53; p = 0.44). Nurse staffing intensity transiently increased during the acquisition year for both AMI and stroke. Interpretation: In a regulated, fixed-price system, acquisitions were significantly associated with reduced AMI mortality and expanded interventional infrastructure. Findings suggest consolidation can improve clinical quality by unlocking capital for life-saving investments. While capital-intensive conditions like AMI benefit rapidly, complex care pathways like stroke likely require additional clinical integration strategies. Funding: German Research Foundation.

Indexed as

Acute myocardial infarctionGermanyHospital acquisitionsQuality of careStroke

Identifiers

PMID42540482
PMCPMC13425888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.