Evidence map›Paper›PMID 42540479›Full record

ArticleMaterials today. Bio2026

Engineering adaptive self-healing biomaterials from jammed microfluidic elastomeric particles.

Jennifer Kieda, Kaitlyn Ramsay, Richard Jiang, Shira Landau, Ramak Khosravi, Chuan Liu, Amid Shakeri, Karl T Wagner, Dhana Abdo, Anna Maria Popovic and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer KiedaUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Kaitlyn RamsayUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Richard JiangUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Shira LandauUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Ramak KhosraviToronto General Hospital Research Institute, Unity Health Network, Toronto, Ontario, M5G 0A3, Canada.
Chuan LiuUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Amid ShakeriUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Karl T WagnerUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Dhana AbdoUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.
Anna Maria PopovicToronto General Hospital Research Institute, Unity Health Network, Toronto, Ontario, M5G 0A3, Canada.
Sean FarleyDepartment of Chemistry, University of Victoria, Victoria, BC, V8W 2Y2, Canada.
Katherine S ElviraDepartment of Chemistry, University of Victoria, Victoria, BC, V8W 2Y2, Canada.
Milica RadisicUniversity of Toronto, Institute of Biomedical Engineering, Toronto, Ontario, M5S 3G9, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomaterials designed for implantation must accommodate the dynamic mechanical and structural environment of the human body. Yet, current strategies for creating materials capable of adapting their shape post-implantation remain limited. In this work, we introduced a remoldable, biodegradable, and biocompatible granular scaffold composed of monodisperse poly(octamethylene maleate (anhydride) citrate) (POMaC) particles. Monodisperse POMaC droplets with controlled diameters were generated using a droplet microfluidic platform, then subsequently jammed and UV-crosslinked to form interconnected, porous, and self-healing elastomeric scaffolds. The scaffold chemical composition and crosslinking parameters directly influenced mechanical properties, stability, and permeability, enabling tunability across a range of tissue engineering applications. The granular scaffold exhibited autonomous self-healing, enhanced molecular diffusivity, and robust cell infiltration, while remaining moldable into prescribed geometries under both

Identifiers

PMID42540479
PMCPMC13425808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.