ArticleRSC advances2026
An rGO-modified all-solid-state tetracaine-selective microsensor with enhanced interfacial stability for rapid pharmaceutical analysis.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
An all-solid-state tetracaine-selective microsensor with enhanced interfacial stability was developed for rapid potentiometric determination of tetracaine in ophthalmic formulations. The sensor was fabricated by depositing a reduced graphene oxide (rGO) ion-to-electron transducing layer onto a glassy carbon substrate, followed by coating with a poly(vinyl chloride)-based ion-selective membrane incorporating tetracaine-tetraphenylborate (TC/TPB) as the electroactive ion-association complex. A corresponding unmodified sensor was fabricated for comparative evaluation. The optimized rGO-modified microsensor exhibited a near-Nernstian slope of 59.1 ± 0.7 mV per decade over the concentration range of 1.0 × 10
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