Evidence map›Paper›PMID 42540305›Full record

ArticleJPGN reports2026

Barriers and facilitators to the national scale-up of a preterm standardised parenteral nutrition system: A mixed-methods evaluation.

Sarah Fenton, Ann-Marie Brennan, Aoife Fleming, Vicki Livingstone, Brendan Murphy, Aileen Murphy, Eugene Dempsey, Ciara Heavin

Abstract read
In one paragraph

Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah FentonThe Irish Centre for Maternal and Child Health Research (INFANT Research Centre) University College Cork Cork Ireland.ORCID https://orcid.org/0009-0004-6280-1708
Ann-Marie BrennanThe Irish Centre for Maternal and Child Health Research (INFANT Research Centre) University College Cork Cork Ireland.
Aoife FlemingSchool of Pharmacy University College Cork Cork Ireland.
Vicki LivingstoneThe Irish Centre for Maternal and Child Health Research (INFANT Research Centre) University College Cork Cork Ireland.
Brendan MurphyThe Irish Centre for Maternal and Child Health Research (INFANT Research Centre) University College Cork Cork Ireland.
Aileen MurphyDepartment of Economics, Cork University Business School University College Cork Cork Ireland.
Eugene DempseyThe Irish Centre for Maternal and Child Health Research (INFANT Research Centre) University College Cork Cork Ireland.
Ciara HeavinCork University Business School University College Cork Cork Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Standardising parenteral nutrition (PN) care for preterm infants is recommended to enhance safety, outcomes and efficiency, however implementation at scale remains challenging. In 2021, Ireland scaled-up a standardised parenteral nutrition (SPN) system comprising SPN formulations and dosing protocol. We evaluate national scale-up to identify contextually relevant factors to optimise implementation. Methods: A sequential explanatory mixed-methods process evaluation was conducted. Phase 1 comprised a cross-sectional survey of healthcare professionals (HCPs) across nine neonatal units (NUs), alongside analysis of PN purchasing data. Phase 2 included a focus group with the national implementation team and semi-structured interviews with HCPs from three NUs. Qualitative data were analysed using framework analysis guided by the Consolidated Framework for Implementation Research. Results: For Phase 1, we analysed 158 survey responses (27.6% response rate). All NUs had adopted the SPN system; 95% HCPs reported 'Always' or 'Often' using the protocol. SPN accounted for 95% of PN purchased nationally, increasing from 56% pre-implementation. Usability and sustainment scores were significantly higher among trained HCPs ( Conclusion: Scale-up of SPN interventions is achievable in practice, however contextual factors influenced how the intervention was used. System-level infrastructure including training and ongoing monitoring is required to optimise implementation and equitable sustainment.

Indexed as

health service researchimplementation scienceneonatal

Identifiers

PMID42540305
PMCPMC13425788

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.