ArticleACS omega2026
Health Risk Assessment of Dietary Arsenic Exposure and Selenium Deficiency in Tibet Based on In Vitro Gastrointestinal Simulation.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The Tibetan Plateau has a distinctive high-As and low-Se geochemical background. This geochemical characteristic can be transferred to the human body via food intake, thereby posing potential health risks. Conventional assessments based only on total elemental concentrations may not reflect the fraction released during gastrointestinal digestion. In this study, the Unified Bioaccessibility Method (UBM) was combined with Monte Carlo simulation to evaluate dietary As exposure and Se intake from typical Tibetan foods. The results showed a low dietary Se/As ratio of 0.80, far below the national average of 4.35. Bioaccessibility-adjusted modeling reduced estimated As exposure, but carcinogenic risk remained above 10
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