ArticleSkin health and disease2026
Real-world single-centre experience of bimekizumab in patients with psoriasis: a 16-week retrospective observational study.
Article in Skin health and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Background: Bimekizumab inhibits interleukin-17A and interleukin-17F. Clinical trials have shown its efficacy in moderate--to-severe plaque psoriasis; however, real-world effectiveness and safety data remain limited. Objectives: To evaluate the real-world effectiveness and safety of bimekizumab in patients with moderate-to-severe plaque psoriasis over 16 weeks in routine clinical practice. Methods: We conducted a single-centre retrospective observational study involving adults diagnosed with moderate-to--severe plaque psoriasis who were administered bimekizumab (320 mg subcutaneously every 4 weeks for 16 weeks). The primary outcomes assessed were ≥90% improvement in Psoriasis Area and Severity Index (PASI 90) and complete clearance (PASI 100) at week 16. Secondary outcomes included ≥ 50% improvement in PASI, ≥75% improvement in PASI, Dermatology Life Quality Index (DLQI) scores and the incidence of adverse events. Results: In total, 86 patients were enrolled. Their mean (SD) age was 44.4 (12.3) years, 53% ( Conclusions: Bimekizumab demonstrated high efficacy in the real-world treatment of moderate-to-severe plaque psoriasis, with a rapid onset of action and improvement in difficult-to-treat areas. The safety profile was favourable.
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Registered trials
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