Evidence map›Paper›PMID 42540036›Full record

ArticleEULAR rheumatology open2026

Temporal incidence and impact of dementia in rheumatoid arthritis: a cohort study.

Angela Marie Chan, Renee Ng, Charles Inderjeeth, Johannes Nossent

Abstract read
In one paragraph

Article in EULAR rheumatology open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angela Marie ChanDepartment of General Medicine, Geronto-Rheumatology, Khoo Teck Puat Hospital, Singapore, Singapore.
Renee NgRheumatology Group, School of Medicine, University of Western Australia, Crawley, WA, Australia.
Charles InderjeethRheumatology Group, School of Medicine, University of Western Australia, Crawley, WA, Australia.
Johannes NossentRheumatology Group, School of Medicine, University of Western Australia, Crawley, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The objective of this study is to address conflicting evidence that chronic inflammation may increase the risk of dementia in patients with rheumatoid arthritis (RA). Methods: Retrospective population-based study using longitudinally linked administrative health data over a 30-year period for ever hospitalised patients with RA (n = 14,041, age 64 years, 67.2% female) and controls (n = 33,785, age 65 years, 65.6% female). Dementia was defined by the International Classification of Diseases codes for Alzheimer's disease (AD), vascular dementia, and nonspecific dementia subtypes. Dementia incidence rate (IR) and mortality rate (MR) per 1000 person-years and comorbidities are reported. Results: During 9.6 years of follow-up, 1463 (10.4%) of patients with RA and 3701 (11%) of controls were diagnosed with dementia at respective age of 83 vs 84 years ( Conclusions: There was no difference in temporal incidence and MRs for dementia between patients with RA and matched controls. These data suggest that there is minimal impact of RA on the frequency and outcome of dementia.

Identifiers

PMID42540036
PMCPMC13425154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.