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ArticleSkin health and disease2026

Bullous pemphigoid in patients who are frail: a case complicated by cerebral nocardiosis and

Simone Landini, Alessandro Magnatta, Alberto Corrà, Elena Biancamaria Mariotti, Valentina Ruffo di Calabria, Luca Sanna, Virginia Corti, Walter Volpi, Lavinia Quintarelli, Raffella Santi and 3 more

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In one paragraph

Article in Skin health and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Simone LandiniSection of Dermatology and Venereology, Department of Health Sciences, University of Florence, Florence, Italy.ORCID https://orcid.org/0009-0007-5416-4392
Alessandro MagnattaSection of Dermatology and Venereology, Department of Health Sciences, University of Florence, Florence, Italy.
Alberto CorràImmunopathology and Rare Skin Diseases Unit, Department of Health Sciences, Azienda USL Toscana Centro (ERN-SKIN), University of Florence, Florence,Italy.ORCID https://orcid.org/0000-0003-0903-4998
Elena Biancamaria MariottiImmunopathology and Rare Skin Diseases Unit, Department of Health Sciences, Azienda USL Toscana Centro (ERN-SKIN), University of Florence, Florence,Italy.
Valentina Ruffo di CalabriaSection of Dermatology and Venereology, Department of Health Sciences, University of Florence, Florence, Italy.
Luca SannaSection of Dermatology and Venereology, Department of Health Sciences, University of Florence, Florence, Italy.
Virginia CortiSection of Dermatology and Venereology, Department of Health Sciences, University of Florence, Florence, Italy.
Walter VolpiImmunopathology and Rare Skin Diseases Unit, Department of Health Sciences, Azienda USL Toscana Centro (ERN-SKIN), University of Florence, Florence,Italy.
Lavinia QuintarelliImmunopathology and Rare Skin Diseases Unit, Department of Health Sciences, Azienda USL Toscana Centro (ERN-SKIN), University of Florence, Florence,Italy.
Raffella SantiSection of Anatomic Pathology, Department of Health Sciences, Azienda USL Toscana Centro, University of Florence, Florence, Italy.
Gioia Di StefanoSection of Anatomic Pathology, Department of Health Sciences, Azienda USL Toscana Centro, University of Florence, Florence, Italy.
Marzia CaproniImmunopathology and Rare Skin Diseases Unit, Department of Health Sciences, Azienda USL Toscana Centro (ERN-SKIN), University of Florence, Florence,Italy.ORCID https://orcid.org/0000-0002-7471-3471
Alice VerdelliImmunopathology and Rare Skin Diseases Unit, Department of Health Sciences, Azienda USL Toscana Centro (ERN-SKIN), University of Florence, Florence,Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bullous pemphigoid (BP) is the most common autoimmune blistering disorder in older patients and is typically managed with long-term immunosuppressive therapy tailored to the patient's comorbidities and overall health. Patients who are frail with concurrent haematological malignancies represent a particularly vulnerable population due to their impaired immunity and treatment-related immunosuppression. We report the case of an 85-year-old man with mantle cell lymphoma, previously treated with rituximab and ibrutinib, who developed BP confirmed by histology, direct immunofluorescence, indirect immunofluorescence and enzyme-linked immunosorbent assay. Initial disease control was achieved with systemic corticosteroids and methotrexate. Subsequently, he developed a subcutaneous thoracic nodule consistent with panniculitis, followed by cerebral nocardiosis and

Identifiers

PMID42540004
PMCPMC13424893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.