Evidence map›Paper›PMID 42540003›Full record

ArticleSkin health and disease2026

Chronic prurigo in an adolescent patient successfully controlled with dupilumab.

Mohammed Nasser Al-Abdulla, Noof Al-Qahtani, Shahd M Younis, Syed Rizvi, Amro Elfaieg, Joerg Buddenkotte, Martin Steinhoff

Abstract readCase Reports
In one paragraph

Article in Skin health and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammed Nasser Al-AbdullaDepartment of Dermatology and Venereology, Hamad Medical Corporation, Doha, Qatar.ORCID https://orcid.org/0009-0004-3048-6213
Noof Al-QahtaniDepartment of Dermatology and Venereology, Hamad Medical Corporation, Doha, Qatar.
Shahd M YounisTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Syed RizviDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
Amro ElfaiegDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
Joerg BuddenkotteDepartment of Dermatology and Venereology, Hamad Medical Corporation, Doha, Qatar.
Martin SteinhoffDepartment of Dermatology and Venereology, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic prurigo, formerly termed prurigo nodularis, is a chronic skin condition characterized by intensely itchy nodules and papules. It primarily affects adults, particularly middle-aged women. The aetiology of chronic prurigo is unclear, but it can be associated with primary skin dermatoses and systemic conditions. Minimal data on chronic prurigo in children are available in the literature. While systemic therapies for chronic prurigo have significant side effects, targeted biologic and small--molecule inhibitors offer a promising treatment option with a good benefit-risk ratio. We report one of the first cases of an adolescent with chronic prurigo that was successfully controlled with dupilumab. Dupilumab treatment resulted in a fast, significant and sustainable improvement in the signs and symptoms of chronic prurigo, with favourable safety and tolerability profiles, highlighting its potential for recalcitrant cases and long-term remission.

Identifiers

PMID42540003
PMCPMC13425074

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.