Evidence map›Paper›PMID 42539968›Full record

ReviewSkin health and disease2026

Comparison of narrowband ultraviolet B with psoralen plus ultraviolet A phototherapy for patients with early-stage mycosis fungoides: a systematic review and meta-analysis.

Serish Bano, F N U Sidra, F N U Venjhraj, Mutahira Asif, Aghna Iman, F N U Fatima, Meva Ram, Aymar Akilimaili

Abstract readReview
In one paragraph

Review in Skin health and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Serish BanoDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
F N U SidraDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
F N U VenjhrajDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
Mutahira AsifDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
Aghna ImanDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
F N U FatimaFederal Medical College, SZABMU, Islamabad, Pakistan.
Meva RamDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
Aymar AkilimailiDepartment of Research, Medical Research Circle (MedReC), Goma, Democratic Republic of the Congo.ORCID https://orcid.org/0000-0001-9393-1215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The most prevalent cutaneous T-cell lymphoma is mycosis fungoides (MF), managed in early stages with psoralen plus ultraviolet A (PUVA) or narrowband ultraviolet B (NB-UVB) phototherapy. Objectives: To evaluate the therapeutic effectiveness and side effect profiles of PUVA vs. NB-UVB in patients with early-stage MF. Method: A systematic review was conducted, incorporating data from nine studies sourced from PubMed, Cochrane and Google Scholar. Eligible studies were those that simultaneously evaluated PUVA and NB-UVB, enrolling at least 10 adult participants per group with histologically confirmed early-stage (IA-IIA) MF and reported treatment outcomes. Exclusions were advanced disease, paediatric patients, noncomparative or nonrelevant treatments, small sample sizes or lack of outcome data. No language restrictions were applied. Key outcomes included any response, complete response, partial response, treatment failure, relapse-free interval and adverse effects. Results: A total of 923 patients (age range 33-71 years; 52.5% men) were included: 556 treated with PUVA and 367 with NB-UVB. Any response was seen in 90.5% of those treated with PUVA vs. 88.3% of patients who received NB-UVB [odds ratio (OR) 1.18, 95% confidence interval (CI) 0.73-1.90; Conclusions: Both PUVA and NB-UVB are effective, but PUVA may be preferred when sustained remission is the primary therapeutic goal.

Identifiers

PMID42539968
PMCPMC13425035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.