ReviewCureus2026
Fatal Administration of Propofol: A Comprehensive Narrative Forensic Review of Propofol Deaths From Accidents, Suicides, and Homicides.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accidental death, suicide, and homicide have resulted from the intravenous injection of propofol. There have been at least 30 accidental victims of propofol self-administration; more than 75% were medical workers who chronically used it as a recreational drug. At least 13 of the 14 individuals who committed suicide by injecting themselves with propofol were either a physician or a nurse. A fatal injection of propofol was used to murder a minimum of 10 people; for many of these deceased persons, neither the drug nor homicide was initially suspected at the time of death. Therefore, the discovery of an intravenous needle mark wound, or additional clinical history, may lead to further evaluation of the death scene or the victim or both and result in the appropriate toxicology studies of the deceased person, which can establish that the cause of death was from propofol and the manner of death was homicide. A meticulous and thorough examination of the cutaneous and mucosal surfaces of a dead person may provide the essential forensic dermatology clue to either the cause of death (which is the specific illness, pathophysiologic aberration, or trauma that results in the individual's dying) or the manner of death (which is the situation of how the death occurred, such as the consequence to an accident, a suicide, a homicide or a natural sequela of disease, aging or bodily malfunctioning) or both. In summary, propofol intravenous injection can result in accidental death, suicide, or homicide; the number of needle mark wounds can be multiple or solitary. A thorough search of the death scene and a comprehensive forensic examination of the victim may be useful in establishing the manner of death when the cause of death has been attributed to propofol injection. The intent of this paper is to provide a comprehensive narrative forensic review of propofol deaths from accidents, suicides, and homicides.
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Registered trials
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