Evidence map›Paper›PMID 42539663›Full record

ArticleFrontiers in medicine2026

Case Report: Necrotizing myositis secondary to a pararectal fistula: diagnostic challenges and multidisciplinary management.

Andrea Neville Cracchiolo, Daniela Maria Palma, Marco Palmeri, Bruno Cracchiolo, Dario Nicosia, Fabio Genco, Luigi Profera, Santi Maurizio Raineri, Giuseppe Accurso

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea Neville CracchioloUnit of 118 Emergency Medical Services and Hyperbaric Medicine, ARNAS Civico Di Cristina Benfratelli Hospital, Palermo, Sicily, Italy.
Daniela Maria PalmaDepartment of Neuroscience and Emergency with Trauma Center, A.O.O.R. Villa Sofia Cervello, Palermo, Italy.
Marco PalmeriUnit of 118 Emergency Medical Services and Hyperbaric Medicine, ARNAS Civico Di Cristina Benfratelli Hospital, Palermo, Sicily, Italy.
Bruno CracchioloVita-Salute San Raffaele University, Milan, Italy.
Dario NicosiaUnit of 118 Emergency Medical Services and Hyperbaric Medicine, ARNAS Civico Di Cristina Benfratelli Hospital, Palermo, Sicily, Italy.
Fabio GencoUnit of 118 Emergency Medical Services and Hyperbaric Medicine, ARNAS Civico Di Cristina Benfratelli Hospital, Palermo, Sicily, Italy.
Luigi ProferaDepartment of Anaesthesia, Intensive Care and Emergency, Policlinico Paolo Giaccone, Palermo, Italy.
Santi Maurizio Raineri *Unit of 118 Emergency Medical Services and Hyperbaric Medicine, ARNAS Civico Di Cristina Benfratelli Hospital, Palermo, Sicily, Italy.
Giuseppe Accurso *Unit of 118 Emergency Medical Services and Hyperbaric Medicine, ARNAS Civico Di Cristina Benfratelli Hospital, Palermo, Sicily, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Necrotizing soft tissue infections (NSTIs) are rare but life-threatening conditions requiring early diagnosis and aggressive multidisciplinary management. Necrotizing myositis (NM) is an uncommon and particularly severe manifestation, often associated with diagnostic delay and poor outcomes. Case presentation: We report the case of a 57-year-old man presenting with mild pelvic pain radiating to the posterior thigh. Contrast-enhanced computed tomography revealed a presacral abscess with an extrasphincteric fistulous tract extending into the posterior thigh musculature. Surgical exploration confirmed necrotizing fasciitis with myonecrosis caused by Group A Streptococcus. The patient underwent repeated surgical debridement, broad-spectrum antimicrobial therapy, and adjunctive hyperbaric oxygen therapy, resulting in progressive clinical improvement and complete recovery at six-month follow-up. Conclusion: This case highlights the importance of early imaging, prompt source control, and multidisciplinary management in atypical NSTIs, while illustrating the potential adjunctive role of HBO

Indexed as

Group A Streptococcushyperbaric oxygen therapynecrotizing myositisnecrotizing soft tissue infectionpararectal fistula

Identifiers

PMID42539663
PMCPMC13424143

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.