ArticleFrontiers in endocrinology2026
Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The relationship between endometrial thickness and adverse pregnancy outcomes has garnered significant attention from researchers. The aim of this study was to investigates whether endometrial thickness (EMT) is a risk factor for hypertensive disorders of pregnancy (HDP) in women undergoing Methods: This single center retrospective cohort study included 2,536 women aged 20-40 years with male-factor infertility who underwent their first frozen-thawed embryo transfer (FET) and had a singleton live birth. Endometrial thickness was measured via transvaginal ultrasound on the day of embryo transfer, and patients were divided into three groups: ≤8 mm, 8-14 mm, and ≥14 mm. The primary outcome was the incidence of HDP. Results: The overall HDP rate was 3.67%, with no significant difference across EMT groups: 3.97% in the ≤ 8 mm group, 3.74% in the 8-14 mm group, and 3.03% in the ≥ 14 mm group (p=0.760). Older maternal age and higher BMI were significant risk factors for HDP [maternal age (OR 1.10, 95% CI 1.05-1.16, p=0.000) and BMI ≥ 24.0 Kg/m² (OR 2.40, 95% CI 1.10-5.25, p=0.028)], while EMT was not associated with HDP risk. Conclusion: Endometrial thickness was not a significant risk factor for HDP in women with male-factor infertility undergoing their first FET.
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