Evidence map›Paper›PMID 42539353›Full record

ArticleNeurotrauma reports

Implications of Polypharmacy to Clinical Practice for Traumatic Spinal Cord Injury: A Population-Based Approach in British Columbia, Canada.

Michael Bond, Aidan Beresford, Vanessa K Noonan, Naama Rotem-Kohavi, Brian K Kwon, Sabrina T Wong, Guiping Liu, Jason M Sutherland

Abstract read
In one paragraph

Article in Neurotrauma reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael BondCentre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada.
Aidan BeresfordCentre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0009-0004-7431-9177
Vanessa K NoonanPraxis Spinal Cord Institute, Vancouver, British Columbia, Canada.
Naama Rotem-KohaviPraxis Spinal Cord Institute, Vancouver, British Columbia, Canada.
Brian K KwonCombined Neurosurgery and Orthopaedic Spine Program, University of British Columbia, Vancouver, BC, Canada.
Sabrina T WongCentre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada.
Guiping LiuCentre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada.
Jason M SutherlandCentre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients living with traumatic spinal cord injury (TSCI) often have multiple medical issues and chronic pain requiring potentially several prescription medications. Taking multiple medications can lead to adverse side effects and drug interactions. The main objective of this study is to measure polypharmacy among TSCI patients over a 20-year period and evaluate associated injury characteristics and clinical factors. This study is a retrospective analysis of a population-based cohort of patients with TSCI between 2001 and 2022. Utilizing linked health care data, patients with TSCI were identified. All community-dispensed medications were identified during the first 365 days after discharge. The cumulative polypharmacy method was utilized (average of ≥5 medications over four quarters of the year). Summary statistics were used to evaluate rates of polypharmacy. A multivariable logistic regression identified demographic and clinical characteristics associated with polypharmacy. A total of 3142 patients were identified, 964 (30.7%) patients had polypharmacy with ≥5 medications averaged per quarter in a 1-year period after discharge from the hospital. Factors associated with polypharmacy were age 65 and older (OR = 3.1,

Indexed as

administrative datapharmaceutical policypolypharmacypopulation datatraumatic spinal cord injury (TSCI)

Identifiers

PMID42539353
PMCPMC13422605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.