Evidence map›Paper›PMID 42539311›Full record

ArticlebioRxiv : the preprint server for biology2026

Early life adversity shapes adult behavior in a free-ranging primate.

Sam K Patterson, Josué E Negron-Del Valle, Daniel Phillips, Angelina Ruiz-Lambides, Cayo Biobank Research Unit, Noah Snyder-Mackler, Lauren J N Brent, James P Higham

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sam K PattersonDepartment of Anthropology, University of Notre Dame; Notre Dame, IN, USA.ORCID 0000-0002-5283-8919
Josué E Negron-Del ValleSchool of Life Sciences, Arizona State University; Tempe, AZ, USA.ORCID 0000-0002-8506-1069
Daniel PhillipsSchool of Life Sciences, Arizona State University; Tempe, AZ, USA.ORCID 0000-0002-8822-4564
Angelina Ruiz-LambidesCaribbean Primate Research Center, University of Puerto Rico; San Juan, Puerto Rico.ORCID 0000-0003-0733-4110
Cayo Biobank Research Unit
Noah Snyder-MacklerSchool of Life Sciences, Arizona State University; Tempe, AZ, USA.ORCID 0000-0003-3026-6160
Lauren J N BrentCentre for Research in Animal Behaviour, University of Exeter; Exeter, United Kingdom.ORCID 0000-0002-1202-1939
James P HighamDepartment of Anthropology, New York University; New York, NY, USA.

Funding

Translational Science InitiativeP40OD012217 · OD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI CARLOS A SARIOL · 2012 to 2026
$40.4M
Social modifiers of the pace of aging across multiple domains and tissuesR01AG060931 · NIA · UNIVERSITY OF WASHINGTON · PI BRENT, LAUREN JOHANNA NICOLE, HIGHAM, JAMES P · 2019 to 2023
$3.6M
Animal Model of Genetics and Social Behavior in Autism Spectrum DisordersR01MH096875 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI PLATT, MICHAEL L · 2012 to 2016
$3.6M
Impacts of hurricanes and social buffering on biological aging in a free-ranging animal modelR01AG084706 · NIA · NEW YORK UNIVERSITY · PI Lauren Johanna Nicole Brent, James P Higham · 2023 to 2026
$2.5M
Neurogenomics of Vulnerability and Resilience to Mental Health Syndromes in Response to Extreme Life EventsR01MH118203 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI PLATT, MICHAEL L · 2019 to 2023
$1.9M
Neurogenetic Model of Social Behavior Heterogeneity in Autism Spectrum DisordersR01MH089484 · NIMH · DUKE UNIVERSITY · PI PLATT, MICHAEL L · 2009 to 2010
$1.6M
Effects of a major natural disaster on the pace of aging in a nonhuman primate modelR56AG071023 · NIA · NEW YORK UNIVERSITY · PI BRENT, LAUREN JOHANNA NICOLE, HIGHAM, JAMES P · 2021 to 2021
$839k
Gene regulatory analysis of social integration and resilience during agingR00AG051764 · NIA · UNIVERSITY OF WASHINGTON · PI SNYDER-MACKLER, NOAH · 2017 to 2019
$746k
NIA NIH HHS R00 AG051764NIA NIH HHS R01 AG060931NIA NIH HHS R01 AG084706NIA NIH HHS R56 AG071023NIH HHS P40 OD012217NIMH NIH HHS R01 MH089484NIMH NIH HHS R01 MH096875NIMH NIH HHS R01 MH118203
6 · The paper itself

Abstract

Early life adversity (ELA) causes lasting psychological and behavioral consequences in humans, with parallel stress and fear responses observed in captive animals. How naturally occurring ELA shapes behavior in non-captive animals remains poorly understood. Investigating these effects across socioecological environments is important for identifying the evolutionary pressures shaping early life sensitivities, and determining whether these behavioral syndromes have deep evolutionary roots. Here, we tested the effects of eight forms of ELA on adult behavior using a large dataset (N=313 males, 346 females) from a free-ranging population of rhesus macaques (

Indexed as

behaviordevelopmentearly life adversityprimatessociality

Identifiers

PMID42539311
PMCPMC13419829

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.