Evidence map›Paper›PMID 42539306›Full record

ArticleWomen's health reports (New Rochelle, N.Y.)

Association Between Adverse Childhood Experiences and Prenatal Pandemic-Related Traumatic Stress.

Mandisa Keswa, Nina Oberman, Joanna Stark, Amy Margolis, Charles F Quesenberry, Kathryn Ridout, Lyndsay A Avalos

Abstract read
In one paragraph

Article in Women's health reports (New Rochelle, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Mandisa KeswaKaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA.
Nina ObermanDivision of Research, Kaiser Permanente Northern California, Pleasanton California, USA.
Joanna StarkDepartment of Obstetrics and Gynecology, Kaiser Permanente Santa Clara Medical Center, Santa Clara, California, USA.
Amy MargolisDepartment of Psychiatry and Behavioral Health, The Ohio State University, Columbus, Ohio, USA.
Charles F QuesenberryDivision of Research, Kaiser Permanente Northern California, Pleasanton California, USA.
Kathryn RidoutKaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA.
Lyndsay A AvalosKaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA.ORCID https://orcid.org/0000-0001-8748-0614

Funding

Comparing the Effects of Prenatal Depression and its Treatment on Developmental Outcomes of the OffspringR01HD101483 · NICHD · KAISER FOUNDATION RESEARCH INSTITUTE · PI AVALOS, LYNDSAY AMMON · 2020 to 2024
$3.3M
NICHD NIH HHS R01 HD101483
6 · The paper itself

Abstract

Background: Adverse childhood experiences (ACEs) are prevalent and have long-term effects on regulation, stress, and health. Given the heightened physiological and psychological vulnerability of pregnancy, early life adversity may increase susceptibility to traumatic stress during crisis, such as the COVID-19 pandemic. Objective: To evaluate associations between maternal ACE exposure and prenatal pandemic-related traumatic stress (PTS) measured by symptom count and domains. Methods: This secondary analysis included baseline data collected from a longitudinal cohort of 424 pregnant individuals receiving prenatal care in Kaiser Permanente Northern California between August 2020 and April 2021. ACEs were measured with the Adverse Childhood Experiences Questionnaire and dichotomized ≥3 versus <3 exposures, and by type (abuse, neglect, household dysfunction, violence in home). PTS was evaluated using the 9-item PTS Scale, capturing intrusion, avoidance, arousal, and dissociation. Linear and log-binomial regression models estimated associations between ACEs and PTS, adjusting for covariates. Results: Participants with ≥3 ACEs reported more traumatic stress symptoms (mean difference [MD]: 1.1; 95% confidence interval [CI]: 0.6,1.7) and significantly higher PTS scores (MD: 3.5; 95% CI: 2.0,5.0). After adjustment, higher ACE exposure was associated with elevated intrusion (risk ratio [RR]: 2.03; 95% CI: 1.34-3.07) and dissociation (RR: 1.54; 95% CI: 1.26-1.88) symptoms. Abuse, neglect, and household dysfunction were independently associated with higher total prenatal PTS scores; abuse and neglect were associated with increased dissociative symptoms, and household dysfunction was associated with higher intrusion and arousal symptoms. Conclusions: Higher ACE exposure was associated with increased prenatal PTS, with distinct risk patterns across ACE domains. Findings underscore the importance of trauma-informed, ACE-aware prenatal care models, especially during public health emergencies.

Indexed as

adverse childhood experiencesdissociationmaternal health servicespregnancypsychologicalstresstrauma and stressor related disorders

Identifiers

PMID42539306
PMCPMC13420388

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.