Evidence map›Paper›PMID 42539162›Full record

ArticlebioRxiv : the preprint server for biology2026

A molecular description of plant cellulose biosynthesis inhibition.

Louis F L Wilson, Chaemyeong Lim, Miguel Ángel Torres, Steve Scheiner, Yueping Wan, Pallinti Purushotham, Ruoya Ho, Jochen Zimmer

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Louis F L WilsonDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Virginia, United States.ORCID 0000-0001-6438-3328
Chaemyeong LimDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Virginia, United States.ORCID 0000-0001-6703-7092
Miguel Ángel TorresCentro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Campus Montegancedo UPM, 28223-Pozuelo de Alarcón (Madrid), Spain.ORCID 0000-0002-0435-1786
Steve ScheinerDepartment of Chemistry and Biochemistry, Utah State University, Logan, Utah, United States.ORCID 0000-0003-0793-0369
Yueping WanDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Virginia, United States.ORCID 0009-0006-4310-7918
Pallinti PurushothamDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Virginia, United States.ORCID 0000-0002-5565-1762
Ruoya HoDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Virginia, United States.ORCID 0000-0002-2369-8443
Jochen ZimmerDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Virginia, United States.ORCID 0000-0002-8423-2882

Funding

UVA molecular electron microscopy core for the Mid-Atlantic regionU24GM116790 · NIGMS · UNIVERSITY OF VIRGINIA · PI GALKIN, VITOLD, SAMSO, MONTSERRAT · 2017 to 2021
$2.9M
Synthesis, secretion and assembly of extracellular complex carbohydrates in Gram-negative bacteriaR35GM144130 · NIGMS · UNIVERSITY OF VIRGINIA · PI Jochen Zimmer · 2022 to 2026
$2.5M
300 keV Liquid Helium Robotic MicroscopeS10RR025067 · NCRR · UNIVERSITY OF VIRGINIA · PI EGELMAN, EDWARD H. · 2009 to 2009
$2.0M
NCRR NIH HHS S10 RR025067NIGMS NIH HHS R35 GM144130NIGMS NIH HHS U24 GM116790
6 · The paper itself

Abstract

Dictating cell growth and morphology, cellulose biosynthesis is intrinsic to plant cell biology. Accordingly, cellulose biosynthesis inhibitors (CBIs) are important herbicides, toxins, and experimental tools. We currently lack mechanistic understanding of CBI activity, preventing engineering of herbicide selectivity and disease immunity. Contrasting classical inhibitors, we unexpectedly identify the unusual

Identifiers

PMID42539162
PMCPMC13419706

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.