Evidence map›Paper›PMID 42538964›Full record

ArticlebioRxiv : the preprint server for biology2026

FOXO/DAF-16 modulates the transcription factor ROR/NHR-23 and inhibits the

Himani Galagali, Matthew J Wirick, Amelia F Alessi, Margaret R Starostik, Priya Balamurugan, Isabella Giudicelli Sims, Laurianne Pene, Ruhi Patel, Suhua Feng, Alison R Frand and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Himani GalagaliDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0001-8983-6397
Matthew J WirickBiochemistry, Cell and Molecular Biology Program, Central Michigan University, Mount Pleasant, MI, USA.
Amelia F AlessiDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Margaret R StarostikDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Priya BalamuruganDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Isabella Giudicelli SimsDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Laurianne PeneDepartment of Biology, Central Michigan University, Mount Pleasant, MI, USA.
Ruhi PatelDepartment of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Suhua FengDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.
Alison R FrandDepartment of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Steven E JacobsenDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.
Xantha KarpBiochemistry, Cell and Molecular Biology Program, Central Michigan University, Mount Pleasant, MI, USA.
John K KimDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.

Funding

Sexual dimorphism of piRNA transcription and target silencing mechanisms in C. elegansR01HD109667 · NICHD · JOHNS HOPKINS UNIVERSITY · PI John Kim · 2022 to 2026
$2.4M
Regulation of stem cell fate by FOXO and RNA binding proteinsR15GM150082 · NIGMS · CENTRAL MICHIGAN UNIVERSITY · PI XANTHA KARP · 2023 to 2026
$1.0M
NICHD NIH HHS R01 HD109667NIGMS NIH HHS R15 GM150082
6 · The paper itself

Abstract

Animals rapidly reprogram gene expression to adapt development to environmental stress. How gene regulatory programs that drive continuous development are repressed during stress-induced developmental arrest remains poorly understood. In

Indexed as

dauerdevelopmental arrestinsulin signaling pathwaymultipotencystress response

Identifiers

PMID42538964
PMCPMC13419435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.