Evidence map›Paper›PMID 42538944›Full record

ArticlebioRxiv : the preprint server for biology2026

Metabolic engineering of

Justin A Hayes, Brent Buchinger, Anna W Lunger, Tanvi Khanvilkar, William Gasparrini, Matthew T Fernez, Madeleine Morrissette, Philip Strandwitz, Abigail N Koppes, Ryan Koppes and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Justin A HayesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.ORCID 0000-0003-2531-8333
Brent BuchingerDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.ORCID 0000-0002-8871-1151
Anna W LungerDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.
Tanvi KhanvilkarDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.
William GasparriniDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.ORCID 0000-0001-6499-4831
Matthew T FernezDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.ORCID 0009-0000-0061-4158
Madeleine MorrissetteHolobiome Inc. 650 Albany St. Boston, MA 02118, USA.ORCID 0000-0002-2311-0152
Philip StrandwitzHolobiome Inc. 650 Albany St. Boston, MA 02118, USA.ORCID 0000-0001-6223-3713
Abigail N KoppesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.ORCID 0000-0003-0433-9290
Ryan KoppesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.ORCID 0000-0002-3376-6358
Benjamin M WoolstonDepartment of Chemical Engineering, Northeastern University, 360 Huntington Ave. Boston, MA 02115, USA.ORCID 0000-0002-6570-2236

Funding

Engineered Probiotics for Closed-Loop Control of Disease-Associated Gut Metabolites in Gut-On-Chip ModelsR21EB033892 · NIBIB · NORTHEASTERN UNIVERSITY · PI WOOLSTON, BENJAMIN MICHAEL · 2022 to 2024
$636k
NIBIB NIH HHS R21 EB033892
6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

host-microbe interactionshydrogen sulfidemetabolic engineering

Identifiers

PMID42538944
PMCPMC13419456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.