Evidence map›Paper›PMID 42538913›Full record

ArticlebioRxiv : the preprint server for biology2026

A highly penetrant

Thomas E Keller, Ci Koehring, Brett R Higgins, Jiajia Yang, Faiza A Siddiqui, Forouzandeh Farsaei, Kami Kim, Thomas V McDonald

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thomas E KellerDivision of Infectious Disease and International Medicine, Department of Internal Medicine, University of South Florida.ORCID 0000-0002-6349-0401
Ci KoehringUSF Health Heart Institute, University of South Florida.
Brett R HigginsDivision of Infectious Disease and International Medicine, Department of Internal Medicine, University of South Florida.ORCID 0000-0003-2006-6704
Jiajia YangUSF Health Heart Institute, University of South Florida.
Faiza A SiddiquiUSF Health Heart Institute, University of South Florida.ORCID 0000-0003-0089-7455
Forouzandeh FarsaeiDivision of Infectious Disease and International Medicine, Department of Internal Medicine, University of South Florida.ORCID 0009-0009-5176-5189
Kami KimDivision of Infectious Disease and International Medicine, Department of Internal Medicine, University of South Florida.ORCID 0000-0003-3384-152X
Thomas V McDonaldUSF Health Heart Institute, University of South Florida.ORCID 0000-0002-6075-0888

Funding

Pleiotropy in LMNA-associated Arrhythmogenic CardiomyopathyR56HL159146 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI MCDONALD, THOMAS V · 2022 to 2022
$569k
NHLBI NIH HHS R56 HL159146
6 · The paper itself

Abstract

Background: Methods: We investigated the Results: In differential gene expression analyses we observed that Discussion: These results implicate perturbed gene expression and pathways that may contribute to the severe phenotypes in

Indexed as

cardiomyocytescardiomyopathyLMNARNA-seq

Identifiers

PMID42538913
PMCPMC13419379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.