Evidence map›Paper›PMID 42538910›Full record

ArticlebioRxiv : the preprint server for biology2026

Molecular Deconstruction of the Medullary Raphe Magnus in the rat: Transcriptional Responses to Repeated Seizures.

Paloma Bittencourt-Silva, Ibrahim Vazirabad, Melissa Eilbes, Luke Zangl, Wasif Osmani, Matthew R Hodges

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paloma Bittencourt-SilvaDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226.
Ibrahim VazirabadDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226.
Melissa EilbesDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226.
Luke ZanglDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226.
Wasif OsmaniDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226.
Matthew R HodgesDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226.ORCID 0000-0002-1692-9055

Funding

Progressive seizure-induced cardiorespiratory dysfunction in a novel mutant rat model of seizure disorderR01HL122358 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HODGES, MATTHEW ROBERT · 2015 to 2024
$4.3M
NHLBI NIH HHS R01 HL122358
6 · The paper itself

Abstract

Sudden Unexpected Death in Epilepsy (SUDEP) is a leading cause of death in patients with epilepsy and is thought to result from dysfunctional and/or failure of cardiorespiratory control systems. Post-mortem brainstem tissue analyses in human SUDEP cases point to reductions in markers of the brainstem serotonin (5-HT) system, which is known as a brainstem center that provides excitatory neuromodulation. We have previously shown in a knockout rat model (SS

Identifiers

PMID42538910
PMCPMC13419380

What OpenQuestion holds

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LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.