Evidence map›Paper›PMID 42536726›Full record

ArticleScience advances2026

Human-inspired time-series health evaluation with an adaptive multimodal electronic skin.

Changhao Xu, Hongkai Zheng, Wenzheng Heng, Ruixiao Liu, John MarionSims, Jiahong Li, Peng Jin, Roland Yingjie Tay, Jihong Min, Guanzhi Wang and 2 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Changhao XuAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-6817-3341
Hongkai ZhengDepartment of Computing + Mathematical Sciences, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0009-0002-1693-0272
Wenzheng HengAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0009-0009-5278-0727
Ruixiao LiuAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0009-0007-4801-438X
John MarionSimsAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0009-0002-7980-7343
Jiahong LiAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0001-7938-9589
Peng JinAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-4952-2606
Roland Yingjie TayAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-3341-0984
Jihong MinAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-5788-1473
Guanzhi WangDepartment of Computing + Mathematical Sciences, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0009-0004-1921-1796
Yisong YueDepartment of Computing + Mathematical Sciences, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0001-9127-1989
Wei GaoAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-8503-4562

Funding

Laser-Engraved Wearable Sweat Sensors to Detect and Monitor Cardiometabolic DiseaseR01HL155815 · NHLBI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GAO, WEI · 2021 to 2025
$2.0M
Develop a wireless, skin-conformable and dual-sensing wearable system in support of voice and upper airway telehealth careR01DC021461 · NIDCD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Wei Gao, Jianyu Li · 2024 to 2026
$1.8M
NHLBI NIH HHS R01 HL155815NIDCD NIH HHS R01 DC021461
6 · The paper itself

Abstract

Electronic skin powered with artificial intelligence could enable next-generation robotic and medical devices, yet integrating multimodal sensors and analyzing heterogeneous, multifrequency time series remain challenging. Most wearable machine learning architectures are time-invariant and trained for a specific task, limiting transfer across modalities and users. We present a multimodal electronic skin that captures diverse physiological signs with an adaptive learning framework that rapidly generalizes to unseen tasks with minimal labeled data. Our streamlined end-to-end framework uses a spectral variational autoencoder to denoise and compress multifrequency biosignals into a shared, unified second-wise latent space that preserves the spectral-temporal structure, followed by a transformer to capture temporal dependencies to support diverse downstream tasks with data-efficient learning. We demonstrate robust adaptation with 94.7% accuracy in activity recognition and 90.2% precision in fatigue assessment across various users and daily activities regardless of device and user variations, highlighting a scalable route to generalized physiological time-series analytics and human performance assessments.

Indexed as

Wearable Electronic DevicesAdaptive AlgorithmsAutoencoderDigital HealthHumansMachine Learning

Identifiers

PMID42536726
PMCPMC13426441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.