Evidence map›Paper›PMID 42536554›Full record

ArticleMedicine2026

Evidence summary of nursing care of arterial drug administration and catheter management for HAIC in hepatocellular carcinoma.

Zuxin Shi, Linqiu Han, Tian He, Mingyan Shen

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zuxin ShiShulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang Province, P.R. China.
Linqiu Han
Tian He

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to summarize and grade the existing evidence on continuous hepatic artery infusion chemotherapy (HAIC) arterial drug administration and catheter care, providing evidence-based guidance for clinical nursing decisions.

methodsUsing the "6S" pyramid model, We searched 10 electronic resources (UpToDate, Joanna Briggs Institute [JBI], Cochrane Library, Web of Science, Embase, PubMed, EBSCOhost Research Platform, China National Knowledge Infrastructure, Wanfang, and SinoMed) and 5 professional organization websites (National Comprehensive Cancer Network, the American Society of Clinical Oncology, the Japan Society of Clinical Oncology, the Oncology Nursing Society, and the Multinational Association of Supportive Care in Cancer/European Society for Medical Oncology) from inception to March 31, 2024. Quality appraisal tools were selected by evidence type: Appraisal of Guidelines for Research and Evaluation II for guidelines, JBI critical appraisal tools for systematic reviews/meta-analyses and JBI standards for expert consensus, and the Critical Appraisal for Summaries of Evidence tool for evidence summaries. Evidence was graded using the JBI levels of evidence (2014).

resultsWe identified 769 records and included 12 publications (1 guideline, 2 systematic reviews, 4 meta-analyses, 2 evidence summaries, and 3 expert consensus documents). A total of 36 evidence statements were organized into 4 domains: HAIC puncture care (8), medication care (15), complication prevention and management (10), and catheter removal care (3). Evidence levels ranged from 1b to 5b.

conclusionThis evidence summary offers clear, graded recommendations to guide continuous arterial drug administration and catheter care in HAIC. The evidence can be used to develop or update local protocols and to support bedside decisions on HAIC drug delivery and catheter management. Implementation should be tailored to local healthcare settings by considering workflow, device availability, staffing capacity, and patient risk profiles to optimize safety and feasibility.

Indexed as

Antineoplastic AgentsCarcinoma, HepatocellularInfusions, Intra-ArterialLiver NeoplasmsHepatic ArteryHumansAntineoplastic AgentsEvidence summaryhepatic artery infusion chemotherapyhepatocellular carcinomanursing care

Identifiers

PMID42536554
PMCPMC13433112

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.