ArticleMedicine2026
Correlation of triglyceride-glucose index with myopia in adolescents: A cross-sectional analysis utilizing NHANES data from 1999 to 2008.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global prevalence of myopia among adolescents is rising. While metabolic factors are known to influence various health outcomes, their relationship with adolescent myopia remains poorly understood. This study aimed to investigate the association between the triglyceride-glucose (TyG) index and myopia severity in adolescents. This cross-sectional study included adolescents aged 12 to 19 years from the National Health and Nutrition Examination Survey (NHANES) 1999 to 2008 cycles. After excluding participants with missing data, 3579 adolescents were included. Weighted multivariable logistic regression, TyG quartile analysis, restricted cubic spline modeling, and subgroup interaction analyses were performed using fasting subsample weights and NHANES survey design variables. Among 3579 adolescents aged 12 to 19 years, the prevalence of myopia was 30.5%. After adjustment, the TyG index was significantly associated with moderate myopia (odds ratio [OR] = 1.68; 95% confidence interval [CI]: 1.07-2.63; P = .024) and high myopia (OR = 2.91; 95% CI: 1.05-8.08; P = .040). Participants in the highest TyG quartile had higher odds of high myopia than those in the lowest quartile (OR = 3.04; 95% CI: 1.05-9.25; P = .042), whereas no significant association was observed for mild myopia. Restricted cubic spline modeling suggested an increasing estimated risk of moderate-to-high myopia at higher TyG levels. Subgroup analyses suggested possible effect modification by sex, race/ethnicity, poverty-to-income ratio, and body mass index, but these findings were exploratory. This cross-sectional NHANES analysis identified an association between a higher TyG index and moderate and high myopia in adolescents aged 12 to 19 years. While these results support further research on metabolic correlates of adolescent myopia, they do not demonstrate causality or define a clinically applicable cutoff.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.