ArticleMedicine2026
The association between dietary index for gut microbiota and colorectal cancer prevalence in US adults: Findings from NHANES 2003 to 2023.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Emerging evidence suggests that diet plays a crucial role in shaping gut microbiota, which may influence the risk of colorectal cancer (CRC). This study examined the association between the dietary index for gut microbiota (DI-GM) and CRC prevalence in a nationally representative sample of US adults. This cross-sectional analysis used data from 31,547 adults aged ≥20 years participating in the National Health and Nutrition Examination Survey 2003 to 2023. Weighted logistic regression models estimated odds ratios and 95% confidence intervals for CRC across DI-GM scores, adjusting for demographic, lifestyle, and clinical factors. The mean age of participants was 46.2 ± 17.1 years, and 316 individuals self-reported a CRC diagnosis. CRC cases had significantly lower DI-GM scores than non-cases (3.7 ± 1.5 vs 4.3 ± 1.7, P < .001). Higher DI-GM scores were inversely associated with CRC prevalence (adjusted odds ratio = 0.89, 95% confidence interval = 0.86-0.98). When analyzed categorically, participants with DI-GM scores ≥6 had 30% lower odds of CRC than those with scores ≤3. Diets that promote a healthier gut microbiota composition are associated with a lower prevalence of CRC.
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