ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2026
A bromocresol green electropolymerized film-modified pencil graphite electrode for sensitive differential pulse voltammetric detection of tinidazole.
Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A novel and highly sensitive electrochemical sensor based on an electropolymerized bromocresol green (BCG) film-modified pencil graphite electrode (poly(BCG)@PGE) was developed for the determination of tinidazole (TNDZ). The electropolymerization of BCG on the electrode surface significantly enhanced the electrochemical response toward TNDZ by improving electron-transfer kinetics and increasing the effective surface area. The fabrication and surface characteristics of the modified electrode were systematically investigated using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and Fourier-transform infrared spectroscopy (FT-IR). The electrochemical behavior of TNDZ was studied using CV and differential pulse voltammetry (DPV). Key experimental parameters affecting sensor performance, including the pH of the electrolyte solution, monomer concentration, and number of electropolymerization cycles, were optimized. Under the optimized conditions, the proposed sensor exhibited a wide linear dynamic range (LDR) from 0.4 to 500 µM for TNDZ determination, with a high sensitivity of 1402 µA·mM
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