ArticleBrain imaging and behavior2026
Exploring the complex relationship between vestibular symptoms and migraine: a resting‑state functional MRI study.
Article in Brain imaging and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to examine the temporal sequence of the appearance of vestibular symptoms and migraine, as well as whether they coexist or not, while assessing their influence on cerebral functional activity. The present investigation is a cross-sectional study. This study included 69 participants from the outpatient headache unit at our hospital who were divided into six groups: 33 patients with vestibular migraine (VM) (12 the onset of migraine was earlier than vertigo, 10 the onset of vertigo was earlier than migraine, 11 vertigo was accompanied with migraine), 9 patients with benign recurrent vertigo (BRV), 14 patients with migraine without aura (MoA), and 13 healthy controls. We compared the differences in spontaneous cerebral functional activity between groups, and used the bilateral thalamus as a seed point to analyze its functional connectivity with the whole brain. The relationship between changed cerebral functional activity and clinical features was compared. We have observed variations in the spontaneous functional activity of the right middle and inferior frontal gyrus among individuals in each group, as well as discrepancies in the functional connectivity of the right superior frontal gyrus with the bilateral thalamus. The severity of vertigo disability exhibits a negative correlation with the functional activity in the right inferior frontal gyrus, while the duration of vertigo demonstrates a positive correlation with the functional activity in the right inferior frontal gyrus. Furthermore, the severity of migraine disability displays a negative correlation with the functional connectivity between the bilateral thalamus and the right superior frontal gyrus. In patients with VM, the temporal relationship between vestibular symptoms and migraine did not have any impact on cerebral functional activity. The functional activity of the right middle and inferior frontal gyrus may be influenced by vestibular stimulation, while headache stimulation could potentially modify the functional connectivity between the bilateral thalamus and the right superior frontal gyrus. These findings suggest that VM may be considered as a distinct disease entity.
Indexed as
Identifiers
42536248What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.