Evidence map›Paper›PMID 42536240›Full record

ArticleAnnals of surgical oncology2026

Development of the Novel G-CMAP Score: A Preoperative Scoring System for Predicting Postoperative Complications After Gastrectomy for Gastric Cancer.

Keisuke Okuno, Masanori Tokunaga, Kei Ishihara, Toyoshi Oda, Toshiro Tanioka, Takashi Shigeno, Taichi Ogo, Kenro Kawada, Hisashi Fujiwara, Yusuke Kinugasa

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Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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10 authors.

Keisuke OkunoDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan. okuno.srg1@tmd.ac.jp.ORCID http://orcid.org/0009-0009-6964-2726
Masanori TokunagaDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Kei IshiharaDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Toyoshi OdaDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Toshiro TaniokaDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Takashi ShigenoDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Taichi OgoDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Kenro KawadaDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Hisashi FujiwaraDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.
Yusuke KinugasaDepartment of Gastrointestinal Surgery, Institute of Science Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative complications after gastrectomy for gastric cancer (GC) increase mortality and delay recovery. Simple, objective tools for preoperative risk stratification using routine data remain limited. This study aimed to develop a clinically practical risk score to predict postoperative complications from standard preoperative laboratory tests.

methodsThe study analyzed the data of 490 patients who underwent curative gastrectomy for GC between January 2017 and September 2025. Preoperative hematologic and biochemical parameters were systematically screened to predict postoperative complications of Clavien-Dindo grade II or higher. A composite predictive scoring system was developed, and model performance was assessed using multivariate logistic regression analysis and bootstrap internal validation.

resultsPostoperative complications of Clavien-Dindo grade II or higher occurred for 89 patients (18%). Based on discriminative performance, the C-reactive protein level, monocyte count, serum albumin level, and prothrombin time-international normalized ratio were identified as independent predictors of postoperative complications. An 8-point scoring system, termed the G-CMAP score, was constructed using odds ratio-based weighting. The G-CMAP score demonstrated modest predictive ability (area under the curve, 0.68) and remained an independent predictor in multivariate analysis (odds ratio, 3.42; 95% confidence interval, 2.08-5.61; P < 0.001). Finally, bootstrap internal validation confirmed good discrimination and calibration, with minimal overfitting.

conclusionsThe G-CMAP score is a simple and objective blood-based tool that enables modest preoperative prediction of postoperative complications after gastrectomy for GC.

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GastrectomyGastric cancerLaboratory testPostoperative complicationPredictive biomarker

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.