Evidence map›Paper›PMID 42536214›Full record

Trial reportHernia : the journal of hernias and abdominal wall surgery2026

Protocol for the mesh matters project: evaluating the efficacy of suture mesh vs. planar mesh in small ventral hernia repair - a randomized, blinded multicenter study.

Vitaly Gameza, Nils Brandenburger, Peter Leutscher, Kathrine Holte

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in Hernia : the journal of hernias and abdominal wall surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07476560 (Mesh Matters), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07476560 narecruitingnot on this map

Mesh Matters: Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia Treatment - a Randomized, Blinded Multicenter Study

TypeinterventionalSponsorRegionshospital NordjyllandRan2026 to 2032Enrolled280ConditionsAbdominal Wall Hernia, Umbilical Hernia Repair, Epigastric Hernia RepairArmsmesh suture, planar mesh
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vitaly GamezaDepartment of Gastrointestinal Surgery, North Denmark Regional Hospital, Bispensgade 37, 9800, Hjoerring, Denmark.
Nils BrandenburgerDepartment of Gastrointestinal Surgery, North Denmark Regional Hospital, Bispensgade 37, 9800, Hjoerring, Denmark.
Peter LeutscherCentre for Clinical Research, North Denmark Regional Hospital, Hjoerring, Denmark.
Kathrine HolteDepartment of Gastrointestinal Surgery, North Denmark Regional Hospital, Bispensgade 37, 9800, Hjoerring, Denmark. k.holte@rn.dk.ORCID http://orcid.org/0009-0004-4680-8344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSmall ventral hernia repair is among the most performed general surgical procedures. Despite the routine use of planar polypropylene mesh, surgical site occurrences (SSO) remain a frequent cause of morbidity, readmission, and patient dissatisfaction. A novel mesh-suture integrates mesh reinforcement with suture-like implantation and may reduce subcutaneous dissection and tissue trauma. The aim of this randomized trial is to investigate differences in SSO, patient-reported outcomes (PROMs) and operation time among patients operated for small ventral hernias either with this novel mesh-suture or planar mesh as well as evaluate potential influence of mesh-suture on wider socio-economic parameters such as return to work and contact with family physician/primary sector as well as long-term occurrence.

methodsA prospective, parallel-group, patient- and assessor-blinded, randomized controlled superiority trial conducted across Danish regional hospitals. Eligible patients undergoing elective repair of small ventral hernias are randomized 1:1 to mesh-suture or planar polypropylene mesh. The primary endpoint is SSO. Secondary endpoints include operative time, patient-reported quality of life (EQ-5D-5L, Abdominal Hernia Q), long-term recurrence, reoperation rates, and socio-economic outcomes. Analysis follows the intention-to-treat principle.

conclusionThis trial evaluates whether mesh-suture reduces wound morbidity while maintaining equivalent durability. Results may inform future standards in ventral hernia repair and device selection.

trial registrationThe study is registered at clinicaltrials.gov om March 16th, 2026 (NCT07476560).

Indexed as

Hernia, VentralHerniorrhaphySurgical MeshSuturesSuture TechniquesDenmarkFemaleHumansOperative TimePatient Reported Outcome MeasuresPolypropylenesProspective StudiesQuality of LifeRecurrenceReoperationTreatment OutcomePolypropylenesPolypropylene meshPROMRandomized trialSurgical techniqueVentral hernia

Identifiers

PMID42536214
PMCPMC13427904

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.