ArticleSurgery today2026
Risk factors for long-term surgical recurrence following ileocecal resection for Crohn's disease.
Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStudies focusing on surgical recurrence of Crohn's disease (CD) after ileocecal resection (ICR) are limited. This study aimed to identify the risk factors for long-term CD surgical recurrence following ICR.
methodsWe retrospectively analyzed 504 patients who underwent ICR for CD between July 2016 and September 2020. The primary outcome was surgical recurrence, and anastomotic recurrence was also evaluated. Survival and associations between clinical factors and outcomes were investigated using Kaplan-Meier analyses and Cox proportional hazards models.
resultsWe observed 76 surgical recurrences with a median follow-up of 75 (67-84 months). The surgical recurrence rate was significantly lower in patients who received prophylactic biologic therapy (P < 0.001). Preoperative anti-TNF exposure (HR, 1.659; 95% CI, 1.029-2.674) and ≥ 2 previous surgeries for CD (HR, 2.236; 95% CI, 1.169-4.277) were associated with an increased risk of surgical recurrence, whereas postoperative biologic prophylaxis was protective against surgical recurrence (HR, 0.206; 95% CI, 0.087-0.488). Primary anastomosis (HR, 0.485; 95% CI, 0.238-0.990) and history of perianal disease (HR, 2.079; 95% CI, 1.011-4.277) were associated with anastomotic surgical recurrence.
conclusionsPostoperative biological prophylaxis significantly reduced long-term surgical recurrence rates after ICR in patients with CD, thus emerging as an independent protective factor.
Indexed as
Identifiers
42536158What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.