Evidence map›Paper›PMID 42536091›Full record

SynthesisSurgical endoscopy2026

Prophylactic pyloric drainage for prevention of delayed gastric conduit emptying following Ivor Lewis esophagectomy: a systematic review with exploratory synthesis.

Pascal Burri, Dimitrios Chatziisaak, Marcel A Schneider, Christian A Gutschow, Kristjan Ukegjini, René Warschkow, Thomas Steffen

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pascal BurriDepartment of Visceral and Transplant Surgery, University Hospital Zurich, CH-8006, Zurich, Switzerland. pascal.burri@usz.ch.ORCID http://orcid.org/0009-0003-3925-6871
Dimitrios ChatziisaakDépartement de Chirurgie, Centre Hospitalier Universitaire Vaudois, CH-1005, Lausanne, Switzerland.
Marcel A SchneiderDepartment of Visceral and Transplant Surgery, University Hospital Zurich, CH-8006, Zurich, Switzerland.
Christian A GutschowDepartment of Visceral and Transplant Surgery, University Hospital Zurich, CH-8006, Zurich, Switzerland.
Kristjan UkegjiniDepartment of Surgery, HOCH St.Gallen, CH-9007, St. Gallen, Switzerland.
René WarschkowDepartment of Surgery, HOCH St.Gallen, CH-9007, St. Gallen, Switzerland.
Thomas SteffenNova Chirurgie, CH-9016, St. Gallen, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDGCE complicates 10-50% of ILE and is associated with prolonged hospital stay, aspiration pneumonia, and impaired quality of life. Several intraoperative drainage techniques have been proposed, but the optimal prophylactic approach remains unclear.

methodsWe searched MEDLINE, Embase, Scopus, and Cochrane (PRISMA 2020; PROSPERO CRD420251025012; SWiM reporting guideline) for studies comparing intraoperative prophylactic pyloric drainage (pyloroplasty, botulinum toxin injection, pyloromyotomy, or mechanical balloon dilation) with no intervention in ILE. Risk of bias was assessed using RoB 2 (randomized trials) and ROBINS-I (non-randomized studies), and certainty of evidence was assessed using the GRADE framework. Pooled estimates were framed as exploratory.

resultsFour studies (n = 739; one RCT, three observational cohorts) were eligible. Pooled DGCE in the no-intervention arms was 32.1% (95% CI 4.4-82.9%; I

conclusionThe current evidence is too sparse and heterogeneous to support routine intraoperative pyloric drainage in ILE. Use of standardized DGCE definitions and adequately powered ILE-restricted randomized trials is required.

Indexed as

DrainageEsophagectomyGastroparesisPostoperative ComplicationsPylorusBotulinum ToxinsHumansPyloromyotomyBotulinum ToxinsBotulinum toxinDGCEIvor Lewis esophagectomyPostoperative complicationsPyloric drainage proceduresPyloroplasty

Identifiers

PMID42536091
PMCPMC13582249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.