SynthesisBritish journal of clinical pharmacology2026
Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis.
Synthesis in British journal of clinical pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis.British journal of clinical pharmacology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
aimsNon-adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence. This review investigated the effectiveness of mHealth interventions in improving OAC adherence.
methodsPubMed, Embase, Cochrane Register and Web of Science were searched from 1/1/2000 to 14/11/2025 using terms identifying mHealth, OACs, medication adherence and randomized controlled trials. Included studies were assessed using the Risk of Bias for Interventional Adherence Studies tool. A narrative synthesis of the findings was undertaken. The study protocol was published in PROSPERO (CRD42022372863).
resultsA total of 2571 studies were screened from which 24 randomized controlled trials met the criteria for inclusion. Adherence was most frequently assessed electronically using smart pill bottles and medication events monitoring systems. Nine of the 13 trials reporting statistically significant improvements in adherence tested smartphone-based apps, telephone calls or text messages to support participants or as medication intake reminders. In terms of methodological quality, studies scored best with respect to randomization and blinding procedures, data analysis and interpretation. Studies scored worst in relation to study design and implementation of procedures and adherence outcome measurement and reporting.
conclusionsmHealth interventions involving smartphone-based apps or telephone and text messages may be effective in improving adherence to OACs. Future research should focus on optimizing the frequency of delivery, content of calls or messages and automation. Research should prioritize larger, longer-term trials with emphasis placed on trial design, conduct and reporting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.