ArticleRenal failure2026
Prognostic value of left ventricular peak strain dispersion for cardiovascular events in patients undergoing maintenance haemodialysis: a single-center retrospective cohort study with propensity score matching.
Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study evaluates the association between baseline left ventricular (LV) peak strain dispersion (PSD) and 3-to-5-year cardiovascular outcomes in patients undergoing maintenance hemodialysis (MHD). This single-center retrospective cohort study screened 586 adult patients undergoing MHD at a tertiary renal unit between January 2018 and December 2020, with follow-up through June 2024. Patients were stratified by baseline PSD at the prespecified cutoff of ≥65 ms. One-to-one propensity score matching (nearest neighbor, caliper: 0.02) using 24 covariates was applied to minimize confounding. The primary outcome was major adverse cardiovascular events (MACE)-a composite of cardiovascular death, nonfatal myocardial infarction, hospitalization for heart failure, nonfatal stroke and sustained ventricular arrhythmia. Secondary outcomes included cardiovascular and all-cause mortality. Survival was analyzed using Kaplan-Meier curves, matched-pair robust Cox proportional hazards models and competing-risk sensitivity analyses. After matching, 336 patients (168 per group) were analyzed, with excellent covariate balance (all standardized mean differences <0.10). Over a median follow-up of 46.8 months, MACE occurred in 64 patients (38.1%) with high PSD and 34 patients (20.2%) with low PSD. High PSD was associated with a higher hazard of MACE (adjusted hazard ratio [aHR]: 2.05, 95% confidence interval [CI]: 1.48-2.84;
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