Evidence map›Paper›PMID 42535805›Full record

ReviewIndian journal of ophthalmology2026

Consensus statement for the diagnosis and management of optic neuritis.

Swati Phuljhele, Rohit Saxena, Rohit Bhatia, Dheeraj Khurana, Taru Dewan, Suman K Meena, Lavanya Gandepalli, Virendra Sachdeva, Jaspreet Sukhija, Digvijay Singh and 9 more

Abstract readConsensus StatementReview
In one paragraph

Review in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Swati PhuljheleDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Rohit SaxenaDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Rohit BhatiaCardiothoracic and Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India.
Dheeraj KhuranaDepartment of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Taru DewanDepartment of Ophthalmology, ABVIMS and Dr Ram Manohar Lohia Hospital, New Delhi, India.
Suman K MeenaDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Lavanya GandepalliDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Virendra SachdevaChild Sight Institute, Nimmagadda Prasad Children's Eye Care Centre, L.V. Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India.
Jaspreet SukhijaDepartment of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Digvijay SinghNoble Eye Care, Gurugram, Haryana, India.
Ankur SinhaMaxivision Eye Care Centre, Jaipur, Rajasthan, India.
Rebika DhimanDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Ambika SelvakumarDepartment of Neuro-Ophthalmology, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Mahesh KumarDepartment of Neuro-Ophthalmology, Aravind Eye Hospital, Madurai, Tamil Nadu, India.
Gazella B WarjriDepartment of Ophthalmology , Dr Ram Manohar Lohia Hospital, New Delhi, India.
Akanksha MulayDr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Rashmin GandhiCenter for Sight, Beyond Eye Care, Hyderabad, Telangana, India.
M V Padma SrivastavaCardiothoracic and Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India.
Navin JayakumarDharshan Eye Care, Annanagar, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This consensus statement provides a practical, step-by-step framework designed by 19 national specialists to standardize the care of optic neuritis. Recognizing that clinicians handle these cases differently depending on local resources, the guidelines offer a clear roadmap for distinguishing true optic nerve inflammation from its common clinical mimics. The primary focus is on identifying early "red flags," optimizing neuroimaging protocols, and using targeted cell-based antibody testing to pinpoint the exact cause of the disease. Beyond immediate diagnosis, the paper outlines clear strategies for managing acute episodes with high-dose therapies, handling patients who do not respond to initial steroids, and establishing structured, long-term monitoring plans to track visual recovery. Because delayed or incorrect treatment can lead to permanent, irreversible nerve damage, this document serves as a reliable tool to help ophthalmologists make quick, safe, and effective clinical decisions for patient care.

Indexed as

Disease ManagementOptic NeuritisDiagnosis, DifferentialHumansAquaporin-4 antibodymultiple sclerosismyelin oligodendrocyte glycoproteinneuromyelitis optica spectrum disorderoptic neuritis

Identifiers

PMID42535805
PMCPMC13485077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.