ArticleFrontiers in cardiovascular medicine2026
Non-linear RR interval metrics in canine atrial fibrillation and their relationship to 24-h mean heart rate.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: In both dogs and humans with atrial fibrillation (AF), rate control is monitored using the 24-h Holter mean heart rate (meanHR), which reflects only the central tendency of the RR interval distribution. Naturally occurring canine AF provides a translational model because of its comparable AV nodal physiology and autonomic regulation. Methods: Fifty client-owned dogs with confirmed AF underwent 24-h Holter monitoring. Ten non-linear RR metrics were evaluated: coefficient of variation of RR (CVRR), Poincaré SD1, SD2, SD1/SD2 ratio, |ΔRR|, turning-point ratio, DFA-α, sample entropy, and multiscale entropy (MScEn). The Jensen-gap index ( Results and Discussion: The metrics were partitioned into rate-coupled (CVRR, SD1, SD2, |ΔRR|, DFA-α; |
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