Trial reportFrontiers in pain research (Lausanne, Switzerland)2026
Efficacy of phloroglucinol and diclofenac sodium on pain relief for renal colic due to ureteral stones: a single-center, prospective randomized trial.
Trial report in Frontiers in pain research (Lausanne, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Renal colic is considered one of the most severe types of pain and requires prompt and effective analgesia. This study aimed to evaluate the efficacy of phloroglucinol in treating acute renal colic, comparing it to diclofenac sodium alone and in combination with phloroglucinol. In this single-center, randomized controlled trial, participants with acute renal colic (visual analog scale [VAS] score >4) due to ureterolithiasis were enrolled. They were randomly assigned (1:1:1) to receive diclofenac sodium, phloroglucinol, or a combination of both. The primary outcome was the pain relief rate at 30 min after treatment-defined as the proportion of participants with a ≥ 50% reduction in VAS score from baseline. Of 363 screened participants, 258 were enrolled and completed the trial (86 per group). The primary outcome was significantly better in the diclofenac sodium group than in the phloroglucinol group (55.8% vs. 70.9%; OR, 0.52; 95% CI, 0.28-0.97;
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