ArticleFrontiers in oncology2026
Analysis of misdiagnosis of pancreatic acinar cell carcinoma with significantly elevated alpha-fetoprotein: a case report and literature review.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acinar cell carcinoma (ACC) is a rare malignant exocrine tumor of the pancreas, often presenting with nonspecific symptoms that lead to diagnostic confusion with other pancreatic neoplasms. This article reports a case of a 72-year-old female ACC patient who was misdiagnosed as Solid pseudopapillary neoplasms (SPN) by an external hospital. Laboratory investigations upon admission revealed a markedly elevated serum alpha-fetoprotein (AFP) level of 2321.18 ng/mL, while contrast-enhanced CT of the upper abdomen demonstrated a mass in the pancreatic head, with the liver showing normal parenchyma and no focal masses or lesions. Following a multidisciplinary team (MDT) discussion, the patient underwent a radical Pancreaticoduodenectomy. The final histopathological diagnosis confirmed ACC. This case underscores that in patients with pancreatic masses exhibiting misleading imaging features suggestive of SPN, a significantly elevated serum AFP level should serve as a critical diagnostic clue prompting consideration of ACC. Integrating tumor marker analysis, imaging findings, and MDT evaluation is essential to minimize preoperative misdiagnosis of such rare entities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.