Evidence map›Paper›PMID 42534769›Full record

ArticleFrontiers in oncology2026

Cryoablation as an organ-preserving therapy for low rectal cancer a comprehensive protocol and institutional perspective.

Xuejun Jiang, Feng Zhou, Zujin Ji, Xinyi Lei, Fangjun Yuan

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuejun JiangDepartment of Colorectal and Anal Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Feng ZhouDepartment of Colorectal and Anal Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Zujin JiDepartment of Colorectal and Anal Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Xinyi Lei *Department of Colorectal and Anal Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Fangjun Yuan *Department of General Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryoablation is an interventional approach which induces localized tumor destruction. It is used to treat patients with low rectal cancer (LRC) to preserve their sphincters and avoid permanent colostomies. This article provides a systematic illustration of cryoablation for LRC, encompassing its core technical principles, indications and contraindications. Furthermore, it elaborates on pre-procedural preparation, standardized operative steps, post-cryoablation management, potential complications and mitigation and long-term follow-up protocols. Rooted in five decades of institutional experience, we seek to standardize the procedure and establish it as a credible, evidence-based alternative approach for well-selected patients, especially those who are not candidates for or who decline radical resection.

Indexed as

cryosurgeryimmuneactivationintervention treatmentrectal neoplasmsphincter preservation

Identifiers

PMID42534769
PMCPMC13422206

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.