Evidence map›Paper›PMID 42534757›Full record

SynthesisFrontiers in immunology2026

The evolving landscape of

Yize Fan, Shu Wang, Xingyu Zhu, Xiaotong Zhang, Ce Zhang, Chengshuai Yang, Qiuting Wang, Jiadi Zhao, Dingyuan Guo, Luyuan Ma and 4 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yize Fan *Burns & Wound Healing Center, Hebei Medical University Third Hospital, Shijiazhuang, China.
Shu Wang *Department of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Xingyu Zhu *Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.
Xiaotong ZhangDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Ce ZhangDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Chengshuai YangDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Qiuting WangDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Jiadi ZhaoDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Dingyuan GuoDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Luyuan MaDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Qian ZhaoOffice of Quality Management and Control in Healthcare, Hebei Medical University Third Hospital, Shijiazhuang, China.
Caiyan ZhaoDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.
Jiajia LuDepartment of Orthopedic Trauma, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Chuan ShenDepartment of Infectious Disease, Hebei Medical University Third Hospital & Clinical Research Center for Infectious Disease of Hebei Province & Hebei Key Laboratory for Diagnosis, Treatment, Emergency Prevention and Control of Critical Infectious Diseases, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Publications from 2006 to 2025 were retrieved from the Web of Science Core Collection (WOSCC) and Scopus databases, which formed the core dataset for bibliometric analysis. Clinical trial data were independently supplemented from PubMed to assess translational progress. Multidimensional bibliometric analyses and visualization were performed using R-bibliometrix, VOSviewer and CiteSpace. Results: A total of 1,374 eligible publications were included, with an average annual growth rate of 15.71%, indicating a rapidly expanding field. The research landscape exhibits a hierarchical, stepwise distribution dominated by the United States, with active contributions from multiple countries. Utrecht University and the University of California system were the most prolific institutions. Frontiers-series journals serve as the major publication outlets. Knowledge structure analysis indicates a paradigm shift from fundamental immune mechanisms toward antibiotic resistance, biofilm biology, and immunometabolic regulation. Integration of PubMed clinical data revealed a critical translational gap, as despite advances in mechanistic research, most candidate vaccines and monoclonal antibody therapies failed to meet primary clinical endpoints. Conclusion: Research on

Indexed as

Immune EvasionStaphylococcal InfectionsStaphylococcus aureusAnimalsBibliometricsHumansbibliometricsbiofilmimmune evasionimmunopathogenesisimmunotherapyStaphylococcus aureus

Identifiers

PMID42534757
PMCPMC13422175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.