Evidence map›Paper›PMID 42534682›Full record

ReviewFrontiers in endocrinology2026

Adenosine triphosphate-binding cassette transporters: key players in maintaining fetal health during pregnancy.

Xian-Hong Wang, Ghazala Saeed, Ali Afzal, Umair Ali Khan Saddozai, Gui-Min Shao, Amna Rehman, Syeda Eisha Hamid, Si-Ying Pan, Xin-Ying Ji, Muhammad Babar Khawar

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xian-Hong Wang *Department of Internal Medicine and Pediatrics, Medical School, Henan Provincial Research Center of Engineering Technology for Nuclear Protein Medical Detection, Zhengzhou Health College, Zhengzhou, Henan, China.
Ghazala Saeed *Cell & Molecular Biology Lab, Institute of Zoology, University of the Punjab, Lahore, Pakistan.
Ali Afzal *Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Umair Ali Khan SaddozaiSchool of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University., Yangzhou, China.
Gui-Min ShaoDepartment of Science and Technology, Jinzhong College of Health, Jinzhong, Shanxi, China.
Amna RehmanCell & Molecular Biology Lab, Institute of Zoology, University of the Punjab, Lahore, Pakistan.
Syeda Eisha HamidSchool of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Si-Ying PanDepartment of Obstetrics and Gynecology, Medical School, Henan Provincial Research Center of Engineering Technology for Nuclear Protein Medical Detection, Zhengzhou Health College, Zhengzhou, Henan, China.
Xin-Ying JiDepartment of Microbiology and Immunology, Medical School, Henan Provincial Research Center of Engineering and Technology for Medical Detection of Nuclear Protein, Zhengzhou Health College, Zhengzhou, Henan, China.
Muhammad Babar KhawarSchool of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University., Yangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ATP binding cassette (ABC) transporters are active efflux proteins that move substrates against the gradient via hydrolysis of ATP, and regulate fetal metabolic homeostasis and chemical exposure. The maternal-fetal interface represents a barrier for key transporters involved in xenobiotic efflux, reverse cholesterol transport, bile acid handling, metabolism of steroid hormones and immune tolerance. We combine recent data from cryo-electron microscopy-based structure with recent single-cell transcriptomic data and

Indexed as

ATP-Binding Cassette TransportersFetusPregnancy ComplicationsAnimalsCholestasis, IntrahepaticDiabetes, GestationalFemaleHumansPlacentaPre-EclampsiaPregnancyATP-Binding Cassette TransportersATP-binding cassette transportersfetal healthplacentapreeclampsiapregnancypreterm birth

Identifiers

PMID42534682
PMCPMC13422154

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.