Evidence map›Paper›PMID 42534515›Full record

ArticleJournal of family & reproductive health2026

Antibacterial Activity of DBD Plasma-Activated Saline Against Clinically Relevant Bacteria: Potential Applications in Family and Reproductive Health.

Shervin Goudarzi, Abolfazl Mazandarani

Abstract read
In one paragraph

Article in Journal of family & reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shervin GoudarziPlasma and Nuclear Fusion Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, Iran.
Abolfazl MazandaraniPlasma and Nuclear Fusion Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Effective infection control in family and reproductive healthcare settings is essential for preventing transmission of clinically significant pathogens. Plasma-activated saline (PAS), generated by non-thermal atmospheric-pressure plasma, has emerged as a promising eco-friendly antimicrobial agent due to the generation of reactive oxygen and nitrogen species (RONS). This study evaluated the antibacterial activity of PAS produced by a dielectric barrier discharge (DBD) plasma system and investigated its potential applicability in reproductive and family healthcare environments. Materials and methods: In this experimental study sterile physiological saline was exposed to a DBD plasma system under atmospheric pressure for different activation durations. Antibacterial activity was evaluated against Results: Increasing plasma activation time significantly altered the physicochemical properties of saline, particularly by decreasing pH and increasing reactive nitrogen species concentrations. PAS demonstrated strong time-dependent antibacterial activity against all tested Gram-positive and Gram-negative bacteria. More than 99.9% (>3-log) reduction in viable bacterial counts was achieved after 1 minute of treatment. No detectable bacterial growth was observed after 3 minutes of exposure for Gram-negative bacteria, whereas Conclusion: DBD plasma-activated saline exhibited rapid and substantial antibacterial effects against clinically relevant pathogens associated with infection control. Its potent antimicrobial activity, environmental compatibility, and absence of persistent chemical residues highlight its potential as an alternative disinfectant for medical device sterilization, surface decontamination, and hygiene-related applications.

Indexed as

Antibacterial ActivityFamily HealthInfection ControlNon-Thermal PlasmaPlasma-Activated SalineReactive Oxygen and Nitrogen SpeciesReproductive Health

Identifiers

PMID42534515
PMCPMC13421166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.