Evidence map›Paper›PMID 42534437›Full record

ArticleCureus2026

Proximal Peril From a Distal Malignancy: Impending Colonic Perforation in Obstructing Sigmoid Adenocarcinoma.

Minesh Sindhal, Priyanka Aanandaka, Mohith Vs, Divyeshkumar N Parmar, Anand Kumar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minesh SindhalSurgery, All India Institute of Medical Sciences, Rajkot, Rajkot, IND.
Priyanka AanandakaGeneral Surgery, All India Institute of Medical Sciences, Rajkot, Rajkot, IND.
Mohith VsSurgery, All India Institute of Medical Sciences, Rajkot, Rajkot, IND.
Divyeshkumar N ParmarGeneral Surgery, All India Institute of Medical Sciences, Rajkot, Rajkot, IND.
Anand KumarGeneral Surgery, All India Institute of Medical Sciences, Rajkot, Rajkot, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sigmoid colon adenocarcinoma is a common cause of large bowel obstruction in elderly patients. However, progression to impending proximal colonic perforation due to distal malignant obstruction represents a rare and catastrophic complication associated with high morbidity and mortality. A 74-year-old female presented with acute constipation of five days' duration, progressive abdominal distension, nausea, vomiting, and one episode of fever. Contrast-enhanced computed tomography demonstrated diffuse dilatation of the large bowel, multiple air-fluid levels, and an irregular circumferential wall thickening of the sigmoid colon over a 6-cm segment, causing distal luminal narrowing with marked upstream dilatation and fecalization of the ileum, radiologically consistent with malignant obstruction. Emergency exploratory laparotomy revealed an obstructing sigmoid mass with gross proximal colonic distension and features of impending perforation involving the cecum and hepatic flexure. The patient underwent sigmoid resection with primary anastomosis, extended right hemicolectomy with end-to-side ileo-transverse anastomosis, omentectomy, and thorough peritoneal lavage. Histopathology confirmed a well-differentiated (Grade 1) adenocarcinoma of the sigmoid colon. Distal sigmoid malignancy can precipitate closed-loop large bowel obstruction with progressive proximal colonic dilatation, culminating in impending perforation at remote colonic segments. Early recognition and timely definitive surgical intervention are critical to prevent fatal outcomes.

Indexed as

cecal perforationclosed-loop obstructioncolorectal canceremergency colectomymalignant large bowel obstructionsigmoid adenocarcinoma

Identifiers

PMID42534437
PMCPMC13420287

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.