Evidence map›Paper›PMID 42534434›Full record

ArticleClinical case reports2026

Progressive Cerebellar Dysfunction, Pituitary Insufficiency, and Severe Skeletal Fragility in Adult Survivorship of Childhood Multisystem Langerhans Cell Histiocytosis: A Case Report.

Suhaib Alnahar, Alaa Senjab, Sara Gharib, Zena Gharib, Lama Hadid

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suhaib AlnaharFaculty of Medicine Damascus University Damascus Syrian Arab Republic.ORCID https://orcid.org/0009-0004-0014-7093
Alaa SenjabFaculty of Medicine Damascus University Damascus Syrian Arab Republic.ORCID https://orcid.org/0009-0003-1999-6151
Sara GharibFaculty of Medicine Damascus University Damascus Syrian Arab Republic.ORCID https://orcid.org/0009-0002-0737-7014
Zena GharibFaculty of Medicine Damascus University Damascus Syrian Arab Republic.ORCID https://orcid.org/0009-0008-8178-9053
Lama HadidNational University Hospital Damascus Syrian Arab Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood-onset multisystem Langerhans cell histiocytosis can lead to delayed adult morbidity involving the neurologic, hypothalamic-pituitary, and skeletal systems. Progressive cerebellar dysfunction, chronic pituitary insufficiency, and severe skeletal fragility may emerge years after apparent disease control, underscoring the need for prolonged multidisciplinary follow-up.

Indexed as

central diabetes insipiduscentral hypogonadismcerebellar dysfunctionhypopituitarismLangerhans cell histiocytosissecondary osteoporosis

Identifiers

PMID42534434
PMCPMC13420292

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.