Evidence map›Paper›PMID 42534340›Full record

ReviewReviews in cardiovascular medicine2026

Redefining Sudden Cardiac Death Risk Stratification in Dilated Cardiomyopathy: An Integrative Approach.

Aikaterini-Eleftheria Karanikola, Ioannis Doundoulakis, Christos-Konstantinos Antoniou, Panagiotis Alexandrou, Christos Vosikas, Georgios Leventopoulos, Athanasios Kordalis, Dimitrios Tsiachris, Konstantinos Tsioufis, Konstantinos Gatzoulis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aikaterini-Eleftheria KaranikolaFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0000-0002-9153-5697
Ioannis DoundoulakisFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0000-0003-2184-3296
Christos-Konstantinos AntoniouFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0000-0003-4861-2404
Panagiotis AlexandrouFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0009-0007-5608-4900
Christos VosikasFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0009-0006-8204-7495
Georgios LeventopoulosDepartment of Cardiology, University Hospital of Patras, 26504 Patras, Greece.ORCID https://orcid.org/0000-0002-3982-5101
Athanasios KordalisFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0000-0003-4093-4601
Dimitrios TsiachrisFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0000-0003-4531-9712
Konstantinos TsioufisFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0000-0002-7636-6725
Konstantinos GatzoulisFirst Cardiology Department, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece.ORCID https://orcid.org/0000-0002-6628-0303

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dilated cardiomyopathy (DCM) is one of the most common cardiomyopathy phenotypes. Moreover, sudden cardiac death (SCD) remains a leading cause of mortality in patients with DCM, predominantly driven by malignant ventricular arrhythmias (VAs). Current guideline-recommended risk stratification relies heavily on left ventricular ejection fraction (LVEF) to guide implantable cardioverter-defibrillator (ICD) therapy; however, attention has recently shifted toward a multiparametric strategy that integrates clinical characteristics with electrocardiographic markers, biomarkers, cardiac magnetic resonance (CMR) findings, genetic testing, and electrophysiological studies. This review summarizes current evidence on established and emerging tools for SCD risk stratification in DCM, highlights the limitations of single-parameter approaches, and discusses future directions toward more personalized, dynamic risk assessment to optimize SCD outcomes.

Indexed as

dilated cardiomyopathygenetic testingmagnetic resonance imagingrisk assessmentsudden cardiac deathventricular tachycardia

Identifiers

PMID42534340
PMCPMC13419999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.