ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2026
Impact of hemo-alert program on appropriate antimicrobial therapy in hospitalized patients with bacteremia: a quasi-experimental study.
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To evaluate the impact of the HemoAlert program-a notification system providing pathogen identification and antimicrobial susceptibility results-on the time to initiation of appropriate antimicrobial therapy in patients with bacteremia. Design: Pre-post-quasi-experimental study. Setting: Siriraj Hospital, the largest tertiary care hospital in Bangkok, Thailand. Patients: Adult hospitalized patients with at least one positive blood culture between December 2021-February 2022. Methods: A quasi-experimental study was conducted to assess the impact of the HemoAlert program, which delivered SMS notifications of final microbiology results to the responsible physician and updated the patient's medical record. The primary outcome was the time to appropriate antimicrobial therapy. Secondary outcomes included appropriateness of antimicrobial therapy at 72 and 120 hours, favorable clinical outcome, 28-day mortality, and length of hospital stay. Results: A total of 150 patients were included in both periods. Demographics and pathogen distribution were similar between groups. The most common pathogens were Conclusion: The HemoAlert program improved the timeliness and appropriateness of antimicrobial therapy and enhanced clinical response in patients with bacteremia, supporting the utility of simple notification systems in optimizing management.
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