Evidence map›Paper›PMID 42534206›Full record

ReviewReviews in cardiovascular medicine2026

Long-Term Antithrombotic Therapy After Percutaneous Coronary Intervention: Secondary Prevention Beyond One Year.

Mohamed Abdelgader, Roann Khalid, Kartik Yadav, Sama Ehab Salah Ahmed, Murugapathy Veerasamy, Arka Das, Heerajnarain Bulluck

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed AbdelgaderDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, LS1 3EX Leeds, UK.ORCID https://orcid.org/0009-0003-9030-6272
Roann KhalidGeneral Medicine, King's College Hospital NHS Foundation Trust, SE5 9RS London, UK.ORCID https://orcid.org/0009-0001-4863-5801
Kartik YadavDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, LS1 3EX Leeds, UK.ORCID https://orcid.org/0009-0007-0380-7298
Sama Ehab Salah AhmedDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, LS1 3EX Leeds, UK.ORCID https://orcid.org/0009-0008-8760-3723
Murugapathy VeerasamyDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, LS1 3EX Leeds, UK.ORCID https://orcid.org/0009-0003-6456-1296
Arka DasDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, LS1 3EX Leeds, UK.ORCID https://orcid.org/0000-0003-1134-3036
Heerajnarain BulluckDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, LS1 3EX Leeds, UK.ORCID https://orcid.org/0000-0002-1985-1783

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The early period following percutaneous coronary intervention (PCI), particularly the first days to weeks after stent implantation, is characterized by heightened device-related thrombotic risk, and dual antiplatelet therapy (DAPT) during this phase is well established. With contemporary drug-eluting stents (DES) and abbreviated DAPT strategies, late stent-related events have become less frequent, and long-term risk increasingly reflects underlying systemic atherosclerotic disease. Beyond 12 months, the risk profile shifts further: late events increasingly reflect progressive atherosclerosis and systemic vascular disease rather than stent-related thrombosis. This review synthesizes contemporary evidence on long-term antiplatelet and antithrombotic therapy after PCI, with a focus on the period beyond one year. We evaluate the data supporting for lifelong aspirin as the traditional default strategy, as well as the emerging evidence that P2Y

Indexed as

aspirinclopidogrelcolchicineicosapent ethylmonotherapypercutaneous coronary interventionpharmacogeneticsrivaroxabansecondary preventionthrombosis

Identifiers

PMID42534206
PMCPMC13419996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.